A scientific study on how rats with estrogen deficiency may help scientists in further improving dental implants osseointegration. It is defined as how a living bone connects to an artificial implant.
The study published in the latest issue of the Journal of Oral Implantology revealed that alendronate (ALD), an aminobisphosphonate improves the osseointegration in the rat.
In the study, implants placed in rats with estrogen deficiency did not osseointegrate. The probability of losing the implants at 2 weeks was 50 percent, and at 4 weeks just 13 percent of the implant surface remained in contact with bone. Administration of ALD helped to improve the bone-implant contact to 85 percent of the initial value. None of the implants were lost when ALD was administered, and the quality of the bone density improved to 50 percent. Overall, osseointegration of implants was enhanced by ALD.